A few key pointers for PLO
1. Opponents rarely ever trap for the fear of getting out drawn so they often over play hands like top set etc on any type of drawing board. In these situations little probe bets will get players that missed an easy chance to fold and ones that hit big mash the pot button giving away their hand strength.
2. You want to bet with your draws to the nuts, this way players hanging on to the two pair with a weak flush redraw often think they are good, when if you just check call they often can read your hit draw.
3.DO NOT OVER PLAY AA it is very weak unless you hit a set if you are 3 betting preflop and you will often commit yourself giving your opponents a cheap look at cracking your AA in pot limit and stack you off.
4. Starting hand wise look at hands you can see yourself winning a lot of money with AAKK may be the best looking hand preflop but it rarely makes you much money because often when you hit it reps is on a scary board to other opponents, hands like 6789 double suited or 7789 are the hands that you will win much more money with, these are hands I like to 3 bet with it as it is extremely hard to put you on one like this.
5. Over pairs mean next to nothing to anyone who continues after the flop.
6. Rep the scare card with a small probe bet as stated above, if an someone potted on the flop and you called for whatever reason and a flush completes try to be aggressive with small bets or a small raise players do not suspect bluffing nearly as much as they do as holdem.
There is much more but I can't think of it right now hope this helped!